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Additionally, targeting MK-801 to brain regions expressing GLP-1 receptors avoided the adverse physiological and behavioral effects associated with standalone MK-801 treatment

That difference affects the entire comparison, from what outcomes people expect to how each compound is positioned in research discussions

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Moreover, through the crosstalk with GPCR, insulin activates yes associated protein (YAP) and cMyc to mediate the altered glycolysis induced by KRAS mutation (Hao et al., 2017